• Action mechanisms of small extracellular vesicles in inflammaging 

      Mato Basalo, Rocío; Lucio-Gallego, Sergio; Alarcón-Veleiro, Carmen; Sacristán-Santos, Marta; Miranda Quintana, María del Pilar; Morente López, Miriam; De-Toro, Javier; Silva-Fernández, Lucía; González-Rodríguez, Alba; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2022-04-06)
      [Abstract] The accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging. This biological mechanism relates the development of inflammation ...
    • Effect of miR-21 in mesenchymal stem cells-derived extracellular vesicles behavior 

      Morente-López, Miriam; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Gil, Concha; Carrera, Mónica; Fafián Labora, Juan Antonio; Arufe, M.C. (BioMed Central, 2023-12-21)
      [Abstract] Background: A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the senescence-associated secretory phenotype (SASP) which characterizes ...
    • Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells 

      Alarcón-Veleiro, Carmen; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Vidal-Pampín, Andrea; Quindós-Varela, María; Al-Qatarneh, Thamer; Berrecoso, Germán; Vizoso-Vázquez, Ángel; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2023-01-12)
      [Abstract] Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. The current treatment for EOC involves surgical debulking of the tumors followed by a combination of chemotherapy. While most patients ...
    • Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA 

      Morente-López, Miriam; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Silva-Fernández, Lucía; González-Rodríguez, Alba; De-Toro, Javier; Fafián Labora, Juan Antonio; Arufe, M.C. (Springer, 2022-10-20)
      [Abstract] Osteoarthritis (OA) is closely linked to the increase in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) is implicated in cartilage degradation. In the ...